Arthropathy in acromegaly

The Pituitary-Thyroid Axis in Acromegaly

The pituitary-Thyroid axis of 12 Acromegalic patients was evaluated by measurement of the concentration (Total and free of thyroxine T4, T3 and revers T3 (rT3) and TSH, GH and prolactin before and after in stimulation with TRH. Using an ultra­sensitive method of TSH measurement (IRMA) basal serum TSH levels of patients (0.76, 0.07-l.90mlU/L) were found slightly but significantly (P < 0.01), low...

Hemophilic Arthropathy.

The musculoskeletal manifestations of hemophilia A and B are some of the most common presenting symptoms and continue to be challenging to practitioners. Hemophilic arthropathy, if not initially adequately treated and managed, may lead to debilitating disease and eventually require the consideration of major surgery, including total joint arthroplasty. Thorough comprehension of the pathophysiol...

Acromegaly

Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic, cardiovascular, respiratory, and metabolic...

Acromegaly

Acromegaly is a comparatively rare disease but has attracted the notice of clinicians all over the world on account of the peculiar features associated with it. Within recent years, the finding of an adenomatous growth in the pituitary gland in cases of acromegaly lias focussed a great deal of interest around the subject. This monograph of Dr. Atkinson is therefore likely to be well received by...

Acromegaly.